Early Diagnosis and Monitoring of Neurodegenerative Langerhans Cell Histiocytosis.

TitleEarly Diagnosis and Monitoring of Neurodegenerative Langerhans Cell Histiocytosis.
Publication TypeJournal Article
Year of Publication2015
AuthorsSieni, Elena, Barba Carmen, Mortilla Marzia, Savelli Sara, Grisotto Laura, Di Giacomo Gianpiero, Romano Katiuscia, Fonda Claudio, Biggeri Annibale, Guerrini Renzo, and Aricò Maurizio
JournalPloS one
Volume10
Issue7
Paginatione0131635
Date Published2015
Abstract

Neurodegenerative Langerhans Cell Histiocytosis (ND-LCH) is a rare, unpredictable consequence that may devastate the quality of life of patients cured from LCH. We prospectively applied a multidisciplinary diagnostic work-up to early identify and follow-up patients with ND-LCH, with the ultimate goal of better determining the appropriate time for starting therapy.

DOI10.1016/j.yebeh.2015.06.019
PubMed Link

http://www.ncbi.nlm.nih.gov/pubmed/26176859?dopt=Abstract

Alternate JournalPLoS ONE